## PAM (Dayhoff) matrices

The point accepted mutation (PAM) substitution model, also known as the Dayhoff substitution model, is an amino acid substitution model derived from empirica...

## COMP571 (Fall 2022)

Important note: The information contained in the course syllabus, other than the absence policies, may be subject to change with reasonable advance notice, a...

## Backward algorithm

Like the forward algorithm, we can use the backward algorithm to calculate the marginal likelihood of a hidden Markov model (HMM). Also like the forward algo...